1. unamusedsloth:

NYPD escorting a raccoon out of a beauty salon

Guardians of the Galaxy (2014)

    unamusedsloth:

    NYPD escorting a raccoon out of a beauty salon

    Guardians of the Galaxy (2014)

    (Source: unamusedsloth, via heyfunniest)

  2. helianthi:

    What did the pirate say when he turned 80

    Aye matey

    (via thejackalopegirl)

  3. thefingerfuckingfemalefury:

jasoncanty01:

mylifewithfel:

thespectacularspider-girl:

feignedaffections:

allthingshyper:

gehayi:

hiddlesbatchlove:

forever-falling-forward:

platredeparis:

bnycolew:

mannysiege:

Progress

What

Imma just let this sit here

MOTHA FUCKIN SCIENCE

sources:
Engagdget
DailyTech
CBS

They turned RNA into an anti-virus program. That is amazing.

Let me restate this in case it didn’t sink in the first time
Researchers physically DELETED ALL TRACES of the HIV virus from a human cell.
ALL OF IT.
IF YOU ARE NOT EXCITED ABOUT THAT I DON’T THINK YOU KNOW WHAT HIV IS

Here is the original paper.  My computer at work is currently being an ass.( http://www.hivdent.org/_research_/2014/PNAS-2014-Hu-1405186111.pdf.)
 “Our results also demonstrate, for the first time to our knowledge, that Cas9/gRNA genome editing can be used to immunize cells against HIV-1 infection. The preventative vaccination is independent of HIV-1 strain’s diversity because the system targets genomic sequences regardless of how the viruses enter the infected cells.”
 “Here, we found that LTR-directed gRNA/  Cas9 eradicates the HIV-1 genome and effectively immunizes target cells against HIV-1 reactivation and infection with high specificity and efficiency. These properties may provide a viable path toward a permanent or “sterile” HIV-1 cure, and perhaps provide a means to eradicate and vaccinate against other pathogenic viruses.”
This is beyond awesome.  Not only does it cure HIV infection, it immunizes other cells.  They believe it can be applied to other viral infections where the virus integrates into the host’s genome.

Lets think about this for a second.  HIV was first confirmed in 1959, retroactively, by examining the deceased’s preserved blood.  Between 1960 and 1980, HIV and AIDS are both relatively unknown, with many cases only confirmed retroactively by symptoms or studying the deceased years after their death.
In 1980, we have “Patient Zero” in the USA.  This is when HIV/AIDS became publicly known.
1980.  It is now 2014.  34 years.  It took us only 34 years, from widespread knowledge to this first major step in a cure.  34 years.  Just slightly longer than a generation we have fought HIV to this extent.
And we are only going to get better at it. 

Hey good news for mankind :>

THIS is why we have SCIENCE. This is why we FUND SCIENCE.

This is SUCH important news! <3 

    thefingerfuckingfemalefury:

    jasoncanty01:

    mylifewithfel:

    thespectacularspider-girl:

    feignedaffections:

    allthingshyper:

    gehayi:

    hiddlesbatchlove:

    forever-falling-forward:

    platredeparis:

    bnycolew:

    mannysiege:

    Progress

    What

    Imma just let this sit here

    MOTHA FUCKIN SCIENCE

    sources:

    Engagdget

    DailyTech

    CBS

    They turned RNA into an anti-virus program. That is amazing.

    Let me restate this in case it didn’t sink in the first time

    Researchers physically DELETED ALL TRACES of the HIV virus from a human cell.

    ALL OF IT.

    IF YOU ARE NOT EXCITED ABOUT THAT I DON’T THINK YOU KNOW WHAT HIV IS

    Here is the original paper.  My computer at work is currently being an ass.
    ( http://www.hivdent.org/_research_/2014/PNAS-2014-Hu-1405186111.pdf.)

     “Our results also demonstrate, for the first time to our knowledge, that Cas9/gRNA genome editing can be used to immunize cells against HIV-1 infection. The preventative vaccination is independent of HIV-1 strains diversity because the system targets genomic sequences regardless of how the viruses enter the infected cells.”

     “Here, we found that LTR-directed gRNA/  Cas9 eradicates the HIV-1 genome and effectively immunizes target cells against HIV-1 reactivation and infection with high specificity and efficiency. These properties may provide a viable path toward a permanent orsterileHIV-1 cure, and perhaps provide a means to eradicate and vaccinate against other pathogenic viruses.”

    This is beyond awesome.  Not only does it cure HIV infection, it immunizes other cells.  They believe it can be applied to other viral infections where the virus integrates into the host’s genome.

    Lets think about this for a second.  HIV was first confirmed in 1959, retroactively, by examining the deceased’s preserved blood.  Between 1960 and 1980, HIV and AIDS are both relatively unknown, with many cases only confirmed retroactively by symptoms or studying the deceased years after their death.

    In 1980, we have “Patient Zero” in the USA.  This is when HIV/AIDS became publicly known.

    1980.  It is now 2014.  34 years.  It took us only 34 years, from widespread knowledge to this first major step in a cure.  34 years.  Just slightly longer than a generation we have fought HIV to this extent.

    And we are only going to get better at it. 

    Hey good news for mankind :>

    THIS is why we have SCIENCE. This is why we FUND SCIENCE.

    This is SUCH important news! <3 

    (Source: mannysiege, via thisisfuckingscotland)

  4. r4yquaza:

    shavingryansprivates:

    i think it’s funny that most of the grunge bloggers weren’t even alive at the same time as kurt cobain

    I think it’s funny that most of the text bloggers weren’t even alive at the same time as when anglo-frisian dialects were brought to britain by germanic invaders

    (via thejackalopegirl)

  5. nudqe:

    "white people can’t danc-"

    image

    "white people can’t twer-"

    image

    (via scottishkilt)

  6. peachyprivilege:

video game guy

    peachyprivilege:

    video game guy

    (via thejackalopegirl)

  7. "do i contradict myself?
    very well then i contradict myself,
    i am large, i contain multitudes."
    walt whitman (via theimperfectideal)

    (Source: alexanderguns, via punkrockpatroclus)

  8. thegreenwolf:

    tastefullyoffensive:

    Grass Desk Prank [ohyouperv]

    I could totally be okay with this.

    (via omnibusofhighjinks)

  9. lzbth:

    swag won’t pay the bills but apparently neither will your degree

    (via omnibusofhighjinks)

  10. tonkinsexual:

    I’d like to take a moment to bring to people’s attention what is happening in Scotland right now, more specifically Glasgow. I’m not sure many of you even realise that yesterday we had the chance to vote to be an independent country, and overall, the run up to voting day was fantastic! There was such passion and positivity from both Yes and No camps, but that is now a thing of the past as since the votes have been counted and a NO vote has won 55% to 45% YES. George square has been the hub for many YES gatherings over the past few weeks, and I live in Glasgow and I’ve walked through them, and it’s been a really great atmosphere, but these pictures show what replaces that today. Within 48 hours it has gone from a scene of positivity, to complete anarchy, and the BBC has covered virtually none of it! I ask that you please be aware of the discord going on in Glasgow and Scotland right now, and if you’re in Glasgow please stay at home and be safe, this is not how it should have ended.

    (via thisisfuckingscotland)

  11. alanmorlock:

    Guardians of the Galaxy (1995)

    (via thejackalopegirl)

  12. baracknobama:

    only punks can see this reblog if youre a punk

    (via thejackalopegirl)

  13. pachurz:

    triijunk:

    dorkly:

    The Most Dangerous Gamer

    I’ve been waiting for this joke for ages

    THIS IS A JOKE I NEVER EVEN KNEW I WANTED.

    (via thejackalopegirl)

  14. ask-koki-kariya:

randomfandom121896-2:

ask-koki-kariya:

qorter:

So I found Doug Dimmadome at Dragon Con

You mean Doug Dimmadome owner of the Dimmsdale Dimmadome?

That’s right Doug Dimmadome owner of the Dimmsdale Dimmadome.

Wow I’m your biggest fan, Doug Dimmadome owner of the dimmsdale dimmadome!

    ask-koki-kariya:

    randomfandom121896-2:

    ask-koki-kariya:

    qorter:

    So I found Doug Dimmadome at Dragon Con

    You mean Doug Dimmadome owner of the Dimmsdale Dimmadome?

    That’s right Doug Dimmadome owner of the Dimmsdale Dimmadome.

    Wow I’m your biggest fan, Doug Dimmadome owner of the dimmsdale dimmadome!

    (via thejackalopegirl)

  15. dunwall:

    parcelhare:

    parcelhare:

    I just gave a goblin an accidental handjob in D&D I’m so

    For anyone curious, I tried to rip his dick off and then botched my roll. Now our caravan won’t stop calling me the “Hand of Mercy”

    i

    (via maitresse-atomique)

About

COMMODORE CORNELIUS GIDEON "PUPPERS" BABINGTON III, ESQUIRE

a delightfully distinguished domestic doggy divulges a delectable digest of his dearest diversions

Following